NeoMutate: an ensemble machine learning framework for the prediction of somatic mutations in cancer

NeoMutate: an ensemble machine learning framework for the prediction of somatic mutations in cancer

Abstract Background The accurate screening of tumor genomic landscapes for somatic mutations using high-throughput sequencing involves a crucial step in precise clinical diagnosis and targeted therapy. However, the complex inherent features of cancer tissue, especially, tumor genetic intra-heterogen...

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Bibliographic Details
Main Authors: Irantzu Anzar, Angelina Sverchkova, Richard Stratford, Trevor Clancy
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Medical Genomics
Subjects:
Somatic variant detection
Machine learning
Cancer genomics
Precision medicine
Online Access:http://link.springer.com/article/10.1186/s12920-019-0508-5

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http://link.springer.com/article/10.1186/s12920-019-0508-5

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