Remodeling of B-Cell Subsets in Blood during Pegylated IFNα-2a Therapy in Patients with Chronic Hepatitis B Infection.

Remodeling of B-Cell Subsets in Blood during Pegylated IFNα-2a Therapy in Patients with Chronic Hepatitis B Infection.

The ultimate goal of pegylated interferon-alfa-2a (Peg-IFN-α) therapy in chronic hepatitis B (CHB) infection is HBsAg seroconversion. Even though B cells are major mediators of a positive clinical outcome, their modulation during Peg-IFN-α therapy has not yet been described. We investigated here the...

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Bibliographic Details
Main Authors: Caroline Aspord, Juliana Bruder Costa, Marie-Christine Jacob, Tania Dufeu-Duchesne, Inga Bertucci, Noelle Pouget, Ophelie Brevot-Lutton, Fabien Zoulim, Marc Bourliere, Joel Plumas, Vincent Leroy, ANRS HB06 PEGAN study group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4900671?pdf=render

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http://europepmc.org/articles/PMC4900671?pdf=render

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