Intravital Imaging of Vascular Transmigration by the Lyme Spirochete: Requirement for the Integrin Binding Residues of the B. burgdorferi P66 Protein.

Intravital Imaging of Vascular Transmigration by the Lyme Spirochete: Requirement for the Integrin Binding Residues of the B. burgdorferi P66 Protein.

Vascular extravasation, a key step in systemic infection by hematogenous microbial pathogens, is poorly understood, but has been postulated to encompass features similar to vascular transmigration by leukocytes. The Lyme disease spirochete can cause a variety of clinical manifestations, including ar...

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Bibliographic Details
Main Authors: Devender Kumar, Laura C Ristow, Meiqing Shi, Priyanka Mukherjee, Jennifer A Caine, Woo-Yong Lee, Paul Kubes, Jenifer Coburn, George Chaconas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4686178?pdf=render

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http://europepmc.org/articles/PMC4686178?pdf=render

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