Clinical Pharmacology‐Driven Translational Research to Optimize Bedside Therapeutics of Sotalol Therapy

Oral sotalol, used in adults for sinus rhythm control, is initiated at 80 mg b.i.d. and titrated to a maximum safe dose. The US Food and Drug Administration recommends monitoring the corrected QT interval (QTc) for at least 3 days, until steady‐state exposure of the drug is reached, before patient d...

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Bibliographic Details
Main Authors: Elyes Dahmane, Kathy Tang, Jogarao V.S. Gobburu, T. Joseph Mattingly II, Brent N. Reed, Vincent Y. See, Joshuha Ayres, Vijay Ivaturi
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12670