Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30
Abstract Deubiquitinates (DUBs) have been suggested as novel promising targets for cancer therapies. Accumulating experimental evidence suggests that some metal compounds have the potential to induce cancer cell death via inhibition of DUBs. We previously reported that auranofin, a gold(I)-containin...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-021-00599-6 |