Bcl2 negatively regulates Protective Immune Responses During Mycobacterial Infection

Bcl2 negatively regulates Protective Immune Responses During Mycobacterial Infection

We previously reported that M. tb on its own as well as together with HIV inhibits macrophage apoptosis by upregulating the expression of Bcl2 and Inhibitor of Apoptosis (IAP). In addition, recent reports from our lab showed that stimulation of either macrophages or BMDCs results in the significant...

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Bibliographic Details
Main Authors: Singh Aayushi, Anang Vandana, Verma Chaitenya, Saraswati Shakuntala Surender Kumar, Rana Ankush Kumar, Bandyopadhyay Upasana, Chadha Attinder, Natarajan Krishnamurthy
Format: Article
Language:English
Published: De Gruyter 2021-07-01
Series:Biomolecular Concepts
Subjects:
bcl2
m. bovis bcg
autophagy
immune responses
bacterial burden
Online Access:https://doi.org/10.1515/bmc-2021-0010

Internet

https://doi.org/10.1515/bmc-2021-0010

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