Extensive polycistronism and antisense transcription in the mammalian Hox clusters.
The Hox clusters play a crucial role in body patterning during animal development. They encode both Hox transcription factor and micro-RNA genes that are activated in a precise temporal and spatial sequence that follows their chromosomal order. These remarkable collinear properties confer functional...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-04-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0000356 |