Loss of phosphoinositide 3-kinase γ decreases migration and activation of phagocytes but not T cell activation in antigen-induced arthritis

Loss of phosphoinositide 3-kinase γ decreases migration and activation of phagocytes but not T cell activation in antigen-induced arthritis

<p>Abstract</p> <p>Background</p> <p>Phosphoinositide 3-kinase γ (PI3Kγ) has been depicted as a major regulator of inflammatory processes, including leukocyte activation and migration towards several chemokines. This study aims to explore the role of PI3Kγ in the murine...

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Bibliographic Details
Main Authors: Wetzker Reinhard, Gajda Mieczyslaw, König Christian, Rose Christina, Gruen Michael, Bräuer Rolf
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Musculoskeletal Disorders
Online Access:http://www.biomedcentral.com/1471-2474/11/63

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