Loss of phosphoinositide 3-kinase γ decreases migration and activation of phagocytes but not T cell activation in antigen-induced arthritis

<p>Abstract</p> <p>Background</p> <p>Phosphoinositide 3-kinase γ (PI3Kγ) has been depicted as a major regulator of inflammatory processes, including leukocyte activation and migration towards several chemokines. This study aims to explore the role of PI3Kγ in the murine...

Full description

Bibliographic Details
Main Authors: Wetzker Reinhard, Gajda Mieczyslaw, König Christian, Rose Christina, Gruen Michael, Bräuer Rolf
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Musculoskeletal Disorders
Online Access:http://www.biomedcentral.com/1471-2474/11/63