Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells
Abstract Background Our understanding of the multiple roles exosomes play during tumor progression is still very poor and the contribution of the normal tissue derived exosomes in distant seeding and tumor outgrowth has also not been widely appreciated. Methods Using our all-human liver microphysiol...
Main Authors: | Nikolina Dioufa, Amanda M. Clark, Bo Ma, Colin H. Beckwitt, Alan Wells |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-11-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12943-017-0740-6 |
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