Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells

Abstract Background Our understanding of the multiple roles exosomes play during tumor progression is still very poor and the contribution of the normal tissue derived exosomes in distant seeding and tumor outgrowth has also not been widely appreciated. Methods Using our all-human liver microphysiol...

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Bibliographic Details
Main Authors: Nikolina Dioufa, Amanda M. Clark, Bo Ma, Colin H. Beckwitt, Alan Wells
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Molecular Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12943-017-0740-6