The cellular niche for intestinal stem cells: a team effort

Abstract The rapidly self-renewing epithelium in the mammalian intestine is maintained by multipotent intestinal stem cells (ISCs) located at the bottom of the intestinal crypt that are interspersed with Paneth cells in the small intestine and Paneth-like cells in the colon. The ISC compartment is a...

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Bibliographic Details
Main Authors: Guoli Zhu, Jiulong Hu, Rongwen Xi
Format: Article
Language:English
Published: SpringerOpen 2021-01-01
Series:Cell Regeneration
Subjects:
Online Access:https://doi.org/10.1186/s13619-020-00061-5