Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis

Heterocycles containing difluoromethyl groups are molecules with potential application in pharmaceutical, agricultural and materials science. Here, the authors show an organophotocatalytic difluoromethylation of heterocycles using O2 as green oxidant and preliminarily study the products’ bioactivity...

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Bibliographic Details
Main Authors: Wei Zhang, Xin-Xin Xiang, Junyi Chen, Chen Yang, Yu-Liang Pan, Jin-Pei Cheng, Qingbin Meng, Xin Li
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14494-8