OM2, a Novel Oligomannuronate-Chromium(III) Complex, Promotes Mitochondrial Biogenesis and Lipid Metabolism in 3T3-L1 Adipocytes via the AMPK-PGC1α Pathway.

In our previous studies, we prepared novel oligomannuronate-chromium(III) complexes (OM2, OM4) from marine alginate, and found that these compounds sensitize insulin action better than oligomannuronate(OM), chromium, and metformin in C2C12 skeletal muscle cells. In the present study, we studied thei...

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Bibliographic Details
Main Authors: Jiejie Hao, Cui Hao, Lijuan Zhang, Xin Liu, Xiaolin Zhou, Yunlou Dun, Haihua Li, Guangsheng Li, Xiaoliang Zhao, Yuanyuan An, Jiankang Liu, Guangli Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4503612?pdf=render