Retrotransposon-centered analysis of piRNA targeting shows a shift from active to passive retrotransposon transcription in developing mouse testes

<p>Abstract</p> <p>Background</p> <p>Piwi-associated RNAs (piRNAs) bind transcripts from retrotransposable elements (RTE) in mouse germline cells and seemingly act as guides for genomic methylation, thereby repressing the activity of RTEs. It is currently unknown if and...

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Bibliographic Details
Main Author: Mourier Tobias
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/12/440