The Mutational and Transcriptional Landscapes of Hepatocarcinogenesis in a Rat Model

The Mutational and Transcriptional Landscapes of Hepatocarcinogenesis in a Rat Model

Summary: Hepatocellular carcinoma (HCC) initiation is characterized by stepwise accumulation of molecular alterations, during which the early events are largely unknown. Here, we presented a comprehensive genomic and transcriptomic landscape at stages of hepatitis, cirrhosis, and HCC by using a diet...

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Bibliographic Details
Main Authors: Zhiao Chen, Shengli Li, Mengting Shen, Xinyuan Lu, Chunyang Bao, Di Chen, Jie Ding, Qifeng Wang, Shenglin Huang, Wenming Cong, Leng Han, Xianghuo He
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:iScience
Subjects:
Genomics
Cancer Systems Biology
Cancer
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220308828

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http://www.sciencedirect.com/science/article/pii/S2589004220308828

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