Prefrontal projections to the thalamic nucleus reuniens mediate fear extinction

Previous work has shown that the thalamic nucleus reuniens (RE) is involved in memory and emotion. Here the authors report that the RE and its inputs from the medial prefrontal cortex are indispensable for the top-down inhibition of fear memories after extinction.

Bibliographic Details
Main Authors: Karthik R. Ramanathan, Jingji Jin, Thomas F. Giustino, Martin R. Payne, Stephen Maren
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06970-z