Differences in the stability of the plasmids of Yersinia pestis cultures in vitro: impact on virulence

Plasmid and chromosomal genes encode determinants of virulence for Yersinia pestis, the causative agent of plague. However, in vitro, Y. pestis genome is very plastic and several changes have been described. To evaluate the alterations in the plasmid content of the cultures in vitro and the impact o...

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Bibliographic Details
Main Authors: TC Leal-Balbino, NC Leal, CV Lopes, AMP de Almeida
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2004-11-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000700011