Effects of Hypoxia on the Immunomodulatory properties of Adipose tissue-derived Mesenchymal Stem Cells

Adipose tissue-derived mesenchymal stem cells (ASC) are of great interest as a cellular therapeutic agent for regenerative and immunomodulatory purposes. The function of ASC adapts to environmental conditions, such as oxygen tension. Oxygen levels within tissues are typically much lower than under s...

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Bibliographic Details
Main Authors: M eRoemeling-Van Rhijn, F KF Mensah, S S Korevaar, M JC Leijs, G JVM van Osch, J NM IJzermans, M GH Betjes, C C Baan, W eWeimar, M J Hoogduijn
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00203/full