Diacylglycerol kinase ε deficiency preserves glucose tolerance and modulates lipid metabolism in obese mice[S]

Diacylglycerol kinase ε deficiency preserves glucose tolerance and modulates lipid metabolism in obese mice[S]

Diacylglycerol kinases (DGKs) catalyze the phosphorylation and conversion of diacylglycerol (DAG) into phosphatidic acid. DGK isozymes have unique primary structures, expression patterns, subcellular localizations, regulatory mechanisms, and DAG preferences. DGKε has a hydrophobic segment that promo...

Full description

Bibliographic Details
Main Authors: Louise Mannerås-Holm, Milena Schönke, Joseph T. Brozinick, Laurène Vetterli, Hai-Hoang Bui, Philip Sanders, Emmani B.M. Nascimento, Marie Björnholm, Alexander V. Chibalin, Juleen R. Zierath
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Journal of Lipid Research
Subjects:
lipid kinase
lipidomics
insulin resistance
muscle
animal models
obesity
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520338268

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520338268

Similar Items