α-Cyperone Attenuates H2O2-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2

α-Cyperone Attenuates H2O2-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2

α-Cyperone, extracted from Cyperus rotundus, has been reported to inhibit microglia-mediated neuroinflammation. Oxidative stress and apoptosis play crucial roles in the course of Parkinson’s disease (PD). PD is a common neurodegenerative disease characterized by selective death of dopaminergic neuro...

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Bibliographic Details
Main Authors: Bingxu Huang, Juxiong Liu, Shoupeng Fu, Yufei Zhang, Yuhang Li, Dewei He, Xin Ran, Xuan Yan, Jian Du, Tianyu Meng, Xiyu Gao, Dianfeng Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pharmacology
Subjects:
α-cyperone
oxidative stress
apoptosis
ROS
Nrf2
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00281/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00281/full

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