Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression.

Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression.

ALC1 (amplified in liver cancer 1), an SNF2 superfamily chromatin-remodeling factor also known as CHD1L (chromodomain helicase/ATPase DNA binding protein 1-like), is implicated in base-excision repair, where PARP (Poly(ADP-ribose) polymerase) mediated Poly(ADP-ribose) signaling facilitates the recru...

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Bibliographic Details
Main Authors: Masato Ooka, Takuya Abe, Kosai Cho, Kaoru Koike, Shunichi Takeda, Kouji Hirota
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5800655?pdf=render

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http://europepmc.org/articles/PMC5800655?pdf=render

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