Induction of protective immunity against Schistosoma mansoni infection by antigens purified from PIII, a fraction of adult worm, associated to the downregulation of granuloma formation

Induction of protective immunity against Schistosoma mansoni infection by antigens purified from PIII, a fraction of adult worm, associated to the downregulation of granuloma formation

This study was performed in order to define Schistosoma mansoni antigens able to function as modulator agents in BALB/c mice granulomatous hypersensitivity to parasite egg. The antigens P-24, P-35 and P-97 were purified by affinity chromatography from a fraction of S. mansoni adult worm antigenic pr...

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Bibliographic Details
Main Authors: Gustavson Shauma, Oliveira Sérgio Costa, Alves José Bento, Goes Alfredo Miranda
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1998-01-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Schistosoma mansoni
granuloma modulation
adult worm
immunity
vaccine
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761998000700032

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761998000700032

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