Inflammation and cancer: role of annexin A1 and FPR2/ALX in proliferation and metastasis in human laryngeal squamous cell carcinoma.

The anti-inflammatory protein annexin A1 (ANXA1) has been associated with cancer progression and metastasis, suggesting its role in regulating tumor cell proliferation. We investigated the mechanism of ANXA1 interaction with formylated peptide receptor 2 (FPR2/ALX) in control, peritumoral and tumor...

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Main Authors: Thaís Santana Gastardelo, Bianca Rodrigues Cunha, Luís Sérgio Raposo, José Victor Maniglia, Patrícia Maluf Cury, Flávia Cristina Rodrigues Lisoni, Eloiza Helena Tajara, Sonia Maria Oliani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4260827?pdf=render