Cancer risk associated single nucleotide polymorphisms of mitochondrial D-loop and 8-hydroxy-2'-deoxyguanosine levels in gastric cancer

Cancer risk associated single nucleotide polymorphisms of mitochondrial D-loop and 8-hydroxy-2'-deoxyguanosine levels in gastric cancer

The accumulation of mutations and single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) is related to gastric carcinogenesis. To evaluate the potential relationships between DNA damage and D-loop SNPs, we measured the 8-hydroxy-2'-deoxyguanosine (...

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Bibliographic Details
Main Authors: Yingnan Wang, Yufei Zhao, Yue Zhao, Xiaoxu Luo, Zhanjun Guo, Ruixing Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2017-03-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
8-OHdG
mtDNA
D-loop
SNPs
gastric cancer
Online Access:http://dx.doi.org/10.1080/13102818.2016.1270173

Internet

http://dx.doi.org/10.1080/13102818.2016.1270173

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