Autotaxin expression and its connection with the TNF-alpha-NF-κB axis in human hepatocellular carcinoma

<p>Abstract</p> <p>Background</p> <p>Autotaxin (ATX) is an extracellular lysophospholipase D that generates lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC). Both ATX and LPA have been shown to be involved in many cancers. However, the functional role of A...

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Bibliographic Details
Main Authors: Saxena Romil, Yu Menggang, Zhao Zhenwen, Sheng Hongmiao, Skill Nicholas J, Xu Yan, Wu Jian-Min, Maluccio Mary A
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/71