MSI-Testing in Hereditary Non-Polyposis Colorectal Carcinoma (HNPCC)

Genomic instability at simple repeated sequences, termed microsatellite instability (MSI), plays an important role in the analysis of sporadic and hereditary colon cancers. In hereditary non-polyposis colorectal cancer syndrome (HNPCC) more than 90% of cases show MSI, whereas only 10–15% of sporadic...

Full description

Bibliographic Details
Main Authors: Annegret Müller, Tina Bocker Edmonston, Wolfgang Dietmaier, Reinhard Büttner, Richard Fishel, Josef Rüschoff
Format: Article
Language:English
Published: Hindawi Limited 2004-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2004/343976