Fatigue in Multiple Sclerosis: General and Perceived Fatigue Does Not Depend on Corticospinal Tract Dysfunction

Background: Multiple sclerosis (MS) is an autoimmune disorder of the CNS in which inflammation, demyelination, and axonal damage of the central nervous system coexist. Fatigue is one of the most disabling symptoms in MS and little is known about the neurophysiological mechanisms involved.Methods: To...

Full description

Bibliographic Details
Main Authors: Laura Mordillo-Mateos, Vanesa Soto-Leon, Marta Torres-Pareja, Diego Peinado-Palomino, Nuria Mendoza-Laiz, Carlos Alonso-Bonilla, Michele Dileone, Mario Rotondi, Juan Aguilar, Antonio Oliviero
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00339/full