Changes in predicted protein disorder tendency may contribute to disease risk

<p>Abstract</p> <p>Background</p> <p>Recent studies suggest that many proteins or regions of proteins lack 3D structure. Defined as intrinsically disordered proteins, these proteins/peptides are functionally important. Recent advances in next generation sequencing techn...

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Bibliographic Details
Main Authors: Hu Yang, Liu Yunlong, Jung Jeesun, Dunker A Keith, Wang Yadong
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1752-0509-5-S3-S2