Behavioural Functions and Cerebral Blood Flow in a P301S Tauopathy Mouse Model: A Time-Course Study

Behavioural Functions and Cerebral Blood Flow in a P301S Tauopathy Mouse Model: A Time-Course Study

Tauopathies refer to a group of neurodegenerative diseases with intracellular accumulation of hyperphosphorylated and aggregated microtubule-associated protein tau (MAPT) in neurons and glial cells. PS19 mice bearing the MAPT P301S mutation have been used to mimic human frontotemporal lobar degenera...

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Bibliographic Details
Main Authors: Faraz Ahmad, Hannah Mein, Yu Jing, Hu Zhang, Ping Liu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
tauopathy
PS19 mice
tau
hyperactivity
anxiety
spatial learning and memory
Online Access:https://www.mdpi.com/1422-0067/22/18/9727

Internet

https://www.mdpi.com/1422-0067/22/18/9727

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