GSK-3β and Memory Formation
In Alzheimer’s disease (AD), tau hyperphosphorylation and neurofibrillary tangle (NFT) formation are strongly associated with dementia. Memory impairment is a characteristic, early symptom of AD. Glycogen synthase kinase 3 β (GSK-3β), which is activated in response to amyloid β (Aβ) formation,...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2012-04-01
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| Series: | Frontiers in Molecular Neuroscience |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00047/full |