An integrative analysis of the age-associated multi-omic landscape across cancers

Our understanding of the age-related molecular alterations in cancer is still limited. Here, the authors perform a pan-cancer analysis of age-associated genomic, transcriptomic, and epigenetic alterations, linking age-related gene expression changes to age-related DNA methylation alterations

Bibliographic Details
Main Authors: Kasit Chatsirisupachai, Tom Lesluyes, Luminita Paraoan, Peter Van Loo, João Pedro de Magalhães
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22560-y