A Metal-Free Regioselective Multicomponent Approach for the Synthesis of Free Radical Scavenging Pyrimido-Fused Indazoles and Their Fluorescence Studies

A Metal-Free Regioselective Multicomponent Approach for the Synthesis of Free Radical Scavenging Pyrimido-Fused Indazoles and Their Fluorescence Studies

This study deals with a new and efficient metal-free regioselective synthesis of pyrimido-fused indazoles with nitrogen ring junction motifs. We have developed a metal-free domino type reaction between 3-aminoindazole, aryl aldehydes and aceotophenones in the presence of KOH/DMF that leads to pyrimi...

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Bibliographic Details
Main Authors: Jeyakannu Palaniraja, Selvaraj Mohana Roopan, G Mokesh Rayalu, Naif Abdullah Al-Dhabi, Mariadhas Valan Arasu
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Molecules
Subjects:
N-fused pyrimidine
Strecker synthesis
A3 coupling
Box-Behnken design (BBD)
fluorescence
Online Access:http://www.mdpi.com/1420-3049/21/11/1571

Internet

http://www.mdpi.com/1420-3049/21/11/1571

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