Cyclosporin A induces cardiac differentiation but inhibits hemato-endothelial differentiation of P19 cells.

Little is known about the mechanisms underlying the effects of Cyclosporin A (CsA) on the fate of stem cells, including cardiomyogenic differentiation. Therefore, we investigated the effects and the molecular mechanisms behind the actions of CsA on cell lineage determination of P19 cells. CsA induce...

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Main Authors: Seung-Cheol Choi, Hyunjoo Lee, Ji-Hyun Choi, Jong-Ho Kim, Chi-Yeon Park, Hyung-Joon Joo, Jae-Hyoung Park, Soon-Jun Hong, Cheol-Woong Yu, Do-Sun Lim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4309530?pdf=render