Increased mortality associated with frequent exacerbations in COPD patients with mild-to-moderate lung function impairment, and smokers with normal spirometry

Background: The burden of frequent respiratory exacerbations in COPD patients with mild-to-moderate spirometric impairment and smokers with preserved lung function is unknown. Methods: We categorized COPD participants in COPDGene with post-bronchodilator FEV1%predicted≥50% by the annual exacerbation...

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Bibliographic Details
Main Authors: Spyridon Fortis, Emily S. Wan, Ken Kunisaki, Patrick Tel Eyck, Zuhair K. Ballas, Russell P. Bowler, James D. Crapo, John E. Hokanson, Chris Wendt, Edwin K. Silverman, Alejandro P. Comellas
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Respiratory Medicine: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590143520300129