Decrease in Shiga toxin expression using a minimal inhibitory concentration of rifampicin followed by bactericidal gentamicin treatment enhances survival of <it>Escherichia coli </it>O157:H7-infected BALB/c mice

Decrease in Shiga toxin expression using a minimal inhibitory concentration of rifampicin followed by bactericidal gentamicin treatment enhances survival of <it>Escherichia coli </it>O157:H7-infected BALB/c mice

<p>Abstract</p> <p>Background</p> <p>Treatment of <it>Escherichia coli </it>O157:H7 infections with antimicrobial agents is controversial due to an association with potentially fatal sequelae. The production of Shiga toxins is believed to be central to the p...

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Bibliographic Details
Main Authors: Abdelnoor Alexander M, Sabra Ahmad, Kazzi Natalie, Rahal Elias A, Matar Ghassan M
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
<it>Escherichia coli </it>O157:H7
rifampicin
gentamicin
Shiga toxins
Online Access:http://www.ann-clinmicrob.com/content/10/1/34

Internet

http://www.ann-clinmicrob.com/content/10/1/34

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