Urinary metabolomics reveals the therapeutic effect of HuangQi Injections in cisplatin-induced nephrotoxic rats

Abstract The side effects of cisplatin (CDDP), notably nephrotoxicity, greatly limited its use in clinical chemotherapy. HuangQi Injections (HI), a commonly used preparation of the well-known Chinese herbal medicine Astragali radix, appeared to be promising treatment for nephrotoxicity without compr...

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Bibliographic Details
Main Authors: Chang-Yin Li, Hui-Ting Song, Xiao-Xiao Wang, Yao-Yao Wan, Xuan-Sheng Ding, Shi-Jia Liu, Guo-Liang Dai, Yue-Heng Liu, Wen-Zheng Ju
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03249-z