Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade

Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade

<p>Abstract</p> <p>Background</p> <p>The AMP-activated protein kinase (AMPK) cascade is a sensor of cellular energy charge that acts as a 'metabolic master switch' and inhibits cell proliferation. Activation requires phosphorylation of Thr172 of AMPK within th...

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Bibliographic Details
Main Authors: Alessi Dario R, Mäkelä Tomi P, Mustard Kirsty J, Udd Lina, Reid Jennifer L, Boudeau Jérôme, Hawley Simon A, Hardie D Grahame
Format: Article
Language:English
Published: BMC 2003-09-01
Series:Journal of Biology
Online Access:http://jbiol.com/content/2/4/28

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http://jbiol.com/content/2/4/28

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