Improving Clinical Manufacturing of IL-15 Activated Cytokine-Induced Killer (CIK) Cells

Improving Clinical Manufacturing of IL-15 Activated Cytokine-Induced Killer (CIK) Cells

Cytokine-induced killer (CIK) cells are an immunotherapeutic approach to combat relapse following allogeneic hematopoietic stem cell transplantation (HSCT) in acute leukemia or myelodysplastic syndrome (MDS) patients. Prompt and sequential administration of escalating cell doses improves the efficac...

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Bibliographic Details
Main Authors: Melanie Bremm, Lisa-Marie Pfeffermann, Claudia Cappel, Verena Katzki, Stephanie Erben, Sibille Betz, Andrea Quaiser, Michael Merker, Halvard Bonig, Michael Schmidt, Thomas Klingebiel, Peter Bader, Sabine Huenecke, Eva Rettinger
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
CIK cells
immunotherapy
allogeneic stem cell transplantation
cryopreservation
AB-serum
fresh frozen plasma
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01218/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01218/full

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