Disposition, Metabolism and Histone Deacetylase and Acetyltransferase Inhibition Activity of Tetrahydrocurcumin and Other Curcuminoids

Disposition, Metabolism and Histone Deacetylase and Acetyltransferase Inhibition Activity of Tetrahydrocurcumin and Other Curcuminoids

Tetrahydrocurcumin (THC), curcumin and calebin-A are curcuminoids found in turmeric (Curcuma longa). Curcuminoids have been established to have a variety of pharmacological activities and are used as natural health supplements. The purpose of this study was to identify the metabolism, excretion, ant...

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Bibliographic Details
Main Authors: Júlia T. Novaes, Ryan Lillico, Casey L. Sayre, Kalyanam Nagabushanam, Muhammed Majeed, Yufei Chen, Emmanuel A. Ho, Ana Luísa de P. Oliveira, Stephanie E. Martinez, Samaa Alrushaid, Neal M. Davies, Ted M. Lakowski
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Pharmaceutics
Subjects:
curcumin
tetrahydrocurcumin
calebin-A
UHPLC–MS/MS
pharmacokinetics
antioxidant
anti-inflammatory
anticancer
HDAC
HAT
Online Access:https://www.mdpi.com/1999-4923/9/4/45

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https://www.mdpi.com/1999-4923/9/4/45

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