Quantitative analysis of replication-related mutation and selection pressures in bacterial chromosomes and plasmids using generalised GC skew index

<p>Abstract</p> <p>Background</p> <p>Due to their bi-directional replication machinery starting from a single finite origin, bacterial genomes show characteristic nucleotide compositional bias between the two replichores, which can be visualised through GC skew or (C-G)...

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Bibliographic Details
Main Authors: Suzuki Haruo, Arakawa Kazuharu, Tomita Masaru
Format: Article
Language:English
Published: BMC 2009-12-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/10/640