Detection of Volatile Organic Compounds as Potential Novel Biomarkers for Chorioamnionitis – Proof of Experimental Models

Background: Histologic chorioamnionitis is only diagnosed postnatally which prevents interventions. We hypothesized that volatile organic compounds (VOCs) in the amniotic fluid might be useful biomarkers for chorioamnionitis and that VOC profiles differ between amnionitis of different origins.Method...

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Main Authors: Sybelle Goedicke-Fritz, Thomas Werner, Hendrik J. Niemarkt, Tim G. A. M. Wolfs, Jörg Ingo Baumbach, Matthew W. Kemp, Alan H. Jobe, Tobias Rogosch, Michelle Bous, Elisabeth Kaiser, Regine Stutz, Sascha Meyer, Rolf Felix Maier, Andreas Rembert Koczulla, Owen Brad Spiller, Boris W. Kramer, Michael Zemlin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.698489/full