Molecular characterization of lung dysplasia induced by c-Raf-1.

BACKGROUND:Lung cancer is a multistage process with poor prognosis and high morbidity. Importantly, the genetics of dysplasia, a facultative cancer, at the edge of malignant transformation is unknown. METHODOLOGY/PRINCIPAL FINDINGS:We employed laser microdissection to harvest c-Raf1- induced dysplas...

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Bibliographic Details
Main Authors: Astrid Rohrbeck, Volker Steffen Müller, Jürgen Borlak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2681412?pdf=render