Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease.

BACKGROUND: Inflammatory bowel disease (IBD) is a chronic intestinal disorder that is associated with a limited number of clinical biomarkers. In order to facilitate the diagnosis of IBD and assess its disease activity, we investigated the potential of novel multivariate indexes using statistical mo...

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Main Authors: Tadakazu Hisamatsu, Susumu Okamoto, Masaki Hashimoto, Takahiko Muramatsu, Ayatoshi Andou, Michihide Uo, Mina T Kitazume, Katsuyoshi Matsuoka, Tomoharu Yajima, Nagamu Inoue, Takanori Kanai, Haruhiko Ogata, Yasushi Iwao, Minoru Yamakado, Ryosei Sakai, Nobukazu Ono, Toshihiko Ando, Manabu Suzuki, Toshifumi Hibi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3269436?pdf=render