Akt Kinase Intervenes in Flavivirus Replication by Interacting with Viral Protein NS5

Akt Kinase Intervenes in Flavivirus Replication by Interacting with Viral Protein NS5

Arthropod-borne flaviviruses, such as Zika virus (ZIKV), Usutu virus (USUV), and West Nile virus (WNV), are a growing cause of human illness and death around the world. Presently, no licensed antivirals to control them are available and, therefore, search for broad-spectrum antivirals, including hos...

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Bibliographic Details
Main Authors: Laura Albentosa-González, Nereida Jimenez de Oya, Armando Arias, Pilar Clemente-Casares, Miguel Ángel Martin-Acebes, Juan Carlos Saiz, Rosario Sabariegos, Antonio Mas
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Viruses
Subjects:
flavivirus
replicase
NS5
RNA-dependent RNA-polymerase
PI3K/Akt/mTOR pathway
inhibitors
Online Access:https://www.mdpi.com/1999-4915/13/5/896

Internet

https://www.mdpi.com/1999-4915/13/5/896

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