Co-segregation of hyperactivity, active coping styles and cognitive dysfunction in mice selectively bred for low levels of anxiety

Co-segregation of hyperactivity, active coping styles and cognitive dysfunction in mice selectively bred for low levels of anxiety

We established mouse models of extremes in trait anxiety, which are based on selective breeding for low vs. normal vs. high open-arm exploration on the elevated plus-maze. Genetically selected low anxiety-related behavior (LAB) coincided with hyperactivity in the home cage. Given the fact that sever...

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Bibliographic Details
Main Authors: Yi-Chun eYen, Elmira eAnderzhanova, Mirjam eBunck, Julia eSchuller, Rainer eLandgraf, Carsten T. Wotjak
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Amphetamine
Anxiety
Maternal Behavior
ADHD
hyperactivity
lab
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00103/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00103/full

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