Creation of a novel telomere-cutting endonuclease based on the EN domain of telomere-specific non-long terminal repeat retrotransposon, TRAS1

<p>Abstract</p> <p>Background</p> <p>The ends of chromosomes, termed telomeres consist of repetitive DNA. The telomeric sequences shorten with cell division and, when telomeres are critically abbreviated, cells stop proliferating. However, in cancer cells, by the expres...

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Bibliographic Details
Main Authors: Yoshitake Kazutoshi, Aoyagi Hideyuki, Fujiwara Haruhiko
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Mobile DNA
Online Access:http://www.mobilednajournal.com/content/1/1/13