Place of preoperative treatment of acromegaly with somatostatin analog on surgical outcome: a systematic review and meta-analysis.

CONTEXT: Transsphenoidal neurosurgery is the accepted first-line treatment of acromegaly in the majority of patients. Previous studies addressing preoperative somatostatin analog (SSA) treatment and subsequent surgical cure rates are conflicting, reporting either benefits or no significant differenc...

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Bibliographic Details
Main Authors: Francisco Pita-Gutierrez, Sonia Pertega-Diaz, Salvador Pita-Fernandez, Lara Pena, Gloria Lugo, Susana Sangiao-Alvarellos, Fernando Cordido
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3636268?pdf=render