Back to the Future? The Fallopian Tube, Precursor Escape and a Dualistic Model of High-Grade Serous Carcinogenesis

Beginning with the discovery of the <i>BRCA</i>-associated ovarian cancer susceptibility genes and subsequent detailed examination of risk-reducing salpingo-oophorectomy (RRSO) specimens, a new paradigm of ovarian carcinogenesis has unfolded with attention to the distal fallopian tube. T...

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Bibliographic Details
Main Authors: T. Rinda Soong, David L. Kolin, Nathan J. Teschan, Christopher P. Crum
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/10/12/468