Insects in anthelminthics research: Lady beetle-derived harmonine affects survival, reproduction and stem cell proliferation of Schistosoma mansoni.

Natural products have moved into the spotlight as possible sources for new drugs in the treatment of helminth infections including schistosomiasis. Surprisingly, insect-derived compounds have largely been neglected so far in the search for novel anthelminthics, despite the generally recognized high...

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Bibliographic Details
Main Authors: Josina Kellershohn, Laura Thomas, Steffen R Hahnel, Arnold Grünweller, Roland K Hartmann, Martin Hardt, Andreas Vilcinskas, Christoph G Grevelding, Simone Haeberlein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6436750?pdf=render